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BAL30072

Chemical Structure : BAL30072

CAS No.: 941285-15-0

BAL30072 (BAL 30072)

货号: PC-62571Not For Human Use, Lab Use Only.

BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.
    BAL30072 is also active against many species of MDR isolates of the Enterobacteriaceae family, including isolates that had a class A carbapenemase or a metallo-beta-lactamase.
    BAL30072 trigger the spheroplasting and lysis of Escherichia coli rather than the formation of extensive filaments.

    物理化学性质&存储条件

    分子量 518.472
    分子式 C16H18N6O10S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (aZ)-2-Amino-a-[[(1,4-dihydro-1,5-dihydroxy-4-oxo-2-pyridinyl)methoxy]imino]-N-[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]-4-thiazoleacetamide

    参考文献

    1. Page MG, et al. Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302.

    2. Russo TA, et al. J Antimicrob Chemother. 2011 Apr;66(4):867-73.

    3. Mima T, et al. Int J Antimicrob Agents. 2011 Aug;38(2):157-9.

    4. Hornsey M, et al. Int J Antimicrob Agents. 2013 Oct;42(4):343-6.

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