BAL0891 | TTK/PLK1 inhibitor | Probechem Biochemicals

Chemical Structure : BAL0891

CAS No.: 2734853-80-4

加入收藏

BAL0891 (BAL-0891, Fludarabine-Cl)

货号: PC-22996Not For Human Use, Lab Use Only.

BAL0891 is a first in class, potent dual TTK/PLK1 inhibitor with IC50 of 0.4/46 nM respectively.

规格	价格	库存
5 mg	￥1880	In stock
10 mg	￥2980	In stock
25 mg	￥4980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BAL0891 is a first in class, potent dual TTK/PLK1 inhibitor with IC50 of 0.4/46 nM respectively.
BAL0891 elicits a prolonged effect on TTK, with a transient activity on PLK1.
BAL0891 induces spindle assembly checkpoint (SAC) disruption and aberrant mitotic exit.
BAL0891 elicits potent, single agent antitumor activity in TNBC mouse xenograft models.
BAL0891 synergizes with paclitaxel and carboplatin in mouse TNBC models.

物理化学性质&存储条件

分子量	303.67
分子式	C10H11ClFN5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4S,5S)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(chloromethyl)tetrahydrofuran-3,4-diol

参考文献

1. Elisa Zanini, et al. Front Oncol. 2024 Aug 9:14:1447807.

BAL0891 (BAL-0891, Fludarabine-Cl)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BAL0891 (BAL-0891, Fludarabine-Cl)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.