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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Apamin
Apamin

Chemical Structure : Apamin

CAS No.: 24345-16-2

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Apamin (Apamine)

货号: PC-26170Not For Human Use, Lab Use Only.

Apamin (Apamine) is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Apamin (Apamine) is a peptide neurotoxin found in apitoxin and selective small conductance Ca(2+)-activated K(+) (SK(Ca)) channel blocker, exhibits anti-inflammatory and anti-fibrotic activity.

物理化学性质&存储条件

分子量 2027.34
分子式 C79H131N31O24S4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2 (Disulfide bridge: Cys1-Cys11;Cys3-Cys15)

参考文献

1. Cassell SJ, et al. Elife. 2025 Dec 4;14:RP107733.

2. Veress R, et al. Circ Res. 2025 Jul 18;137(3):386-399.

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