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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Amikacin
Amikacin

Chemical Structure : Amikacin

CAS No.: 37517-28-5

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Amikacin (BAY 41-6551)

货号: PC-25699Not For Human Use, Lab Use Only.

Amikacin (BAY 41-6551) is an aminoglycoside antibiotic that is active against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains (E. coli, MIC=512 ug/mL), induces thioredoxin-interacting protein (TXNIP) up-regulation and suppresses migration and invasion in MDA-MB-231 cells.

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250 mg ￥880 In stock
500 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amikacin (BAY 41-6551) is an aminoglycoside antibiotic that is active against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains (E. coli, MIC=512 ug/mL), induces thioredoxin-interacting protein (TXNIP) up-regulation and suppresses migration and invasion in MDA-MB-231 cells.

物理化学性质&存储条件

分子量 585.61
分子式 C22H43N5O13
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-4-Amino-N-((1R,2S,3S,4R,5S)-5-amino-2-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4-(((2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)-2-hydroxybutanamide

参考文献

1. Fattorini L, et al. Antimicrob Agents Chemother. 1998 Mar;42(3):712-4.

2. Wang YH, et al. Toxics. 2020 Nov 20;8(4):108.

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