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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-Amifostine thiol
Amifostine thiol

Chemical Structure : Amifostine thiol

CAS No.: 31098-42-7

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Amifostine thiol (Amitiotine, WR-1065)

货号: PC-26154Not For Human Use, Lab Use Only.

Amifostine thiol (Amitiotine, WR-1065) is an active metabolite of the cytoprotector Amifostine, which is a broad-spectrum cytoprotective agent and a radioprotector, activates p53 through a JNK-dependent signaling pathway.

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100 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amifostine thiol (Amitiotine, WR-1065) is an active metabolite of the cytoprotector Amifostine, which is a broad-spectrum cytoprotective agent and a radioprotector, activates p53 through a JNK-dependent signaling pathway.

物理化学性质&存储条件

分子量 134.24
分子式 C5H14N2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-Aminopropylamino)ethanethiol

参考文献

1. Jaroslaw Dziegielewski, et al. Free Radic Biol Med. 2008 Dec 15; 45(12): 1674-1681.

2. Olivier Pluquet, et al. J Biol Chem. 2003 Apr 4;278(14):11879-87. J Biol Chem. 2003 Apr 4;278(14):11879-87.

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