Amenamevir (ASP-2151) | Helicase-primase inhibitor | Probechem Biochemicals

Chemical Structure : Amenamevir

CAS No.: 841301-32-4

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Amenamevir (ASP-2151, ASP2151)

货号: PC-60382Not For Human Use, Lab Use Only.

Amenamevir (ASP-2151) is a potent viral helicase-primase inhibitor that possesses antiviral activity against VZV, HSV1 and HSV2 with EC50 of 0.028-0.1 uM.

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5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Amenamevir (ASP-2151) is a potent viral helicase-primase inhibitor that possesses antiviral activity against VZV, HSV1 and HSV2 with EC50 of 0.028-0.1 uM.
Amenamevir (ASP-2151) exerts equipotent activity against VZV, HSV-1 and HSV-2 through prevention of viral DNA replication.
Amenamevir (ASP-2151) also shows activity against aciclovir-resistant VZV.

物理化学性质&存储条件

分子量	482.555
分子式	C24H26N4O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((4-(1,2,4-oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide

参考文献

1. Chono K, et al. J Antimicrob Chemother. 2010 Aug;65(8):1733-41.

2. Himaki T, et al. Antiviral Res. 2012 Feb;93(2):301-4.

3. Katsumata K, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3587-91.

Amenamevir (ASP-2151, ASP2151)

生物&药学活性

物理化学性质&存储条件

参考文献

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Amenamevir (ASP-2151, ASP2151)

生物&药学活性

物理化学性质&存储条件

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