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Adintrevimab

Chemical Structure : Adintrevimab

CAS No.: 2516243-54-0

Adintrevimab (ADG20)

货号: PC-38888Not For Human Use, Lab Use Only.

Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Adintrevimab (ADG20) is a fully human IgG1 monoclonal antibody targeting the highly conserved epitope on the receptor-binding domain (RBD) of S (spike) protein of SARS-CoV-2.
Adintrevimab (ADG20) demonstrated an ability to potently neutralize SARS-CoV-2, including variants of concern, as well as a broad range of sarbecoviruses.
Adintrevimab (ADG20) exhibited broadly neutralizing the entire clade of SARS-like viruses from the sarbecovirus lineage, including diverse family members such as SARS-CoV-1, WIV1, SHC014 and SARS-CoV-2.

Isotype: IgG1-lambda2.
Anti-[human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], human monoclonal antibody.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

参考文献

1. Timothée Bruel, et al. Nat Med. 2022 Mar 23. doi: 10.1038/s41591-022-01792-5.

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