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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-Ac-DNLD-CHO
Ac-DNLD-CHO

Chemical Structure : Ac-DNLD-CHO

CAS No.: 775289-20-8

Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO)

货号: PC-24911Not For Human Use, Lab Use Only.

Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a potent, selective, reversible Caspase-3 inhibitor with IC50 of 9.89 nM, Ki app of 0.68 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a potent, selective, reversible Caspase-3 inhibitor with IC50 of 9.89 nM, Ki app of 0.68 nM respectively.

物理化学性质&存储条件

分子量 501.49
分子式 C20H31N5O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,7S,10S,13S)-7-(2-Amino-2-oxoethyl)-4-(carboxymethyl)-13-formyl-10-isobutyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

参考文献

1. Yoshimori A, et al. BMC Pharmacol. 2007 Jun 27;7:8.

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