Chemical Structure : AZD6280
CAS No.: 942436-93-3
货号: PC-62765Not For Human Use, Lab Use Only.
AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥2880 | In stock | |
| 5 mg | ¥4780 | In stock | |
| 10 mg | ¥7580 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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AZD6280 is a potent, α2/3 functionally selective, partial GABAA receptor modulator with pKi of 7.7.
AZD6280 exerts neutral antagonism at the α1-subunit and partial efficacy at the α2,3-subunits over the α5-subunit.
AZD6280 shows potential for the treatment of anxiety disorders.
| 分子量 | 366.421 | |
| 分子式 | C20H22N4O3 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-amino-8-(2,5-dimethoxyphenyl)-N-propyl-3-cinnolinecarboxamide |
|
1. Jucaite A, et al. Psychopharmacology (Berl). 2017 Feb;234(4):707-716.
2. Chen X, et al. J Clin Psychopharmacol. 2015 Feb;35(1):22-33.
3. Te Beek ET, et al. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54.
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