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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-AZD0022
AZD0022

Chemical Structure : AZD0022

CAS No.: 2958627-18-2

AZD0022 (AZD-0022 )

货号: PC-24666Not For Human Use, Lab Use Only.

AZD0022 is a potent, selective and orally bioavailable inhibitor of KRAS G12D.

规格 价格 库存 数量
25 mg Get quote
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100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AZD0022 is a potent, selective and orally bioavailable inhibitor of KRAS G12D.

物理化学性质&存储条件

分子量 614.65
分子式 C34H30F4N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Naphthalenamine, 4-[4-(3,8-diazabicyclo[3.2.1]oct-6-en-3-yl)-6,8-difluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-7-quinazolinyl]-5-ethynyl-6-fluoro-, (4R)-

参考文献

1. Kevin Beaumont, et al. Cancer Res (2025) 85 (8_Supplement_1): 841.

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