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首页-小分子抑制剂&激动剂-GPCR-Protease-activated Receptor (PAR)-AZ8838
AZ8838

Chemical Structure : AZ8838

CAS No.: 2100285-41-2

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AZ8838 (AZ-8838)

货号: PC-60320Not For Human Use, Lab Use Only.

AZ8838 (AZ-8838) is a potent, and selective, allosteric PAR2 antagonist / negative allosteric modulator (NAM) with Kd of 125 nM.

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5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5280 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AZ8838 (AZ-8838) is a potent, and selective, allosteric PAR2 antagonist / negative allosteric modulator (NAM) with Kd of 125 nM.
AZ-8838 shows excellent selectivity over PAR1 and PAR4 (>50 uM).

物理化学性质&存储条件

分子量 234.274
分子式 C13H15FN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-(4-fluoro-2-propylphenyl)(1H-imidazol-2-yl)methanol

参考文献

1. Cheng RKY, et al. Nature. 2017 May 4;545(7652):112-115.

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