AZ7550 | IGF-1R inhibitor | Probechem Biochemicals

Chemical Structure : AZ7550

CAS No.: 1421373-99-0

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货号: PC-28295Not For Human Use, Lab Use Only.

AZ7550 is a bioactive metabolite of osimertinib, potently inhibits insulin-like growth factor-1 receptor (IGF-1R) with IC50 of 1.6 uM.

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AZ7550 is a bioactive metabolite of osimertinib, potently inhibits insulin-like growth factor-1 receptor (IGF-1R) with IC50 of 1.6 uM.

分子量	485.59
分子式	C27H31N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Methoxy-2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

1. Finlay MR, et al. J Med Chem. 2014 Oct 23;57(20):8249-67.