AUT5

Chemical Structure : AUT5

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货号: PC-27689Not For Human Use, Lab Use Only.

AUT5 is a highly selective positive allosteric modulator of Kv3.1 and Kv3.2 channels, induces positive cooperativity and preferential stabilization of the open state with EC50 of 3.2 uM (Kv3.2).

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100 mg		Get quote

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生物&药学活性

AUT5 is a highly selective positive allosteric modulator of Kv3.1 and Kv3.2 channels, induces positive cooperativity and preferential stabilization of the open state with EC50 of 3.2 uM (Kv3.2).

物理化学性质&存储条件

分子量	365.39
分子式	C20H19N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-3-(6-((2H-spiro[benzofuran-3,1'-cyclopropan]-4-yl)oxy)pyridin-3-yl)-5-ethylimidazolidine-2,4-dione

参考文献

1. Liang Q, et al. Nat Commun. 2024 Mar 21;15(1):2533.

AUT5

生物&药学活性

物理化学性质&存储条件

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AUT5

生物&药学活性

物理化学性质&存储条件

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