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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-CREB/CBP-ATF3W-aeg peptide
ATF3W-aeg peptide

Chemical Structure : ATF3W-aeg peptide

CAS No.:

ATF3W-aeg peptide (ATF3W_aeg)

货号: PC-21905Not For Human Use, Lab Use Only.

ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages.
    Activating transcription factor 3 (ATF3) is an activation transcription factor/cyclic adenosine monophosphate (cAMP) responsive element-binding (CREB) protein family member.
    ATF3 is a stress-induced transcription factor implicated in the modulation of immunity and oncogenesis in various cancers, including prostate, breast, colon, lung, and liver cancers.

    物理化学性质&存储条件

    分子量
    分子式
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    ELAALEQKAYALKQENAALEKEVAALEQKIAALK

    参考文献

    1. Miao Yu, et al. ACS Chem Biol. 2024 Feb 27. doi: 10.1021/acschembio.3c00779.

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