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首页-小分子抑制剂&激动剂-Others-Other Targets-ARUK200282
ARUK200282

Chemical Structure : ARUK200282

CAS No.:

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ARUK200282 (ARUK 200282)

货号: PC-20866Not For Human Use, Lab Use Only.

ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. has broad selectivity against lipid and protein kinases.

物理化学性质&存储条件

分子量 378.86
分子式 C21H19ClN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

CC1=CC=C(N2C=CC3=C(NC4=CC=C(OC)C(Cl)=C4)N=CN=C32)C=C1C

参考文献

1. Henriëtte M G Willems, et al. RSC Med Chem. 2023 Apr 17;14(5):934-946.

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