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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-ARS-2102
ARS-2102

Chemical Structure : ARS-2102

CAS No.: 2098509-21-6

ARS-2102 (ARS2102)

货号: PC-24740Not For Human Use, Lab Use Only.

ARS-2102 is a potent, selective, covalent KRAS G12C inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ARS-2102 is a potent, selective, covalent KRAS G12C inhibitor.

物理化学性质&存储条件

分子量 557.04
分子式 C28H31ClF2N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propen-1-one, 1-[(2R,5S)-4-[6-chloro-2-[3-(dimethylamino)-1-azetidinyl]-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-2,5-dimethyl-1-piperazinyl]-

参考文献

1. Xiaogen Yang, et al. Organic Process Research & Development (2023), 27(1), 206-216.

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