ARN19702 | NAAA inhibitor | Probechem Biochemicals

Chemical Structure : ARN19702

CAS No.: 1971937-18-4

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ARN19702 (ARN-19702)

货号: PC-72101Not For Human Use, Lab Use Only.

ARN19702 (ARN-19702) is potent, selective, orally active, reversible inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 230 nM.

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5 mg	￥1880	In stock
10 mg	￥2880	In stock
25 mg	￥4780	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ARN19702 (ARN-19702) is potent, selective, orally active, reversible inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 230 nM.
ARN19702 produces remarkable protective effects against multiple sclerosis in mice.
ARN19702 reduced nociception associated with paclitaxel-induced neuropathy without development of subacute antinociceptive tolerance.
ARN19702 (30 mg/kg, oral) did not produce place preference or alter exploratory motor behavior in male mice.

物理化学性质&存储条件

分子量	447.543
分子式	C21H22FN3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [2-(ethylsulfonyl)phenyl][(2S)-4-(6-fluoro-2-benzothiazolyl)-2-methyl-1-piperazinyl]-

参考文献

1. Fotio Y, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):70-76.

2. Fotio Y, et al. Psychopharmacology (Berl). 2021 Jan;238(1):249-258.

ARN19702 (ARN-19702)

生物&药学活性

物理化学性质&存储条件

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ARN19702 (ARN-19702)

生物&药学活性

物理化学性质&存储条件

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