AN11736

Chemical Structure : AN11736

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货号: PC-26326Not For Human Use, Lab Use Only.

AN11736 is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.15 nM and 1.3 nM respectively.

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生物&药学活性

AN11736 is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.15 nM and 1.3 nM respectively.
AN11736 demonstrated 100% efficacy with a single dose of 10 mg/kg against both T. congolense and T. vivax in mouse models of infection (IP dosing) and in the target animal, cattle, dosed intramuscularly.

物理化学性质&存储条件

分子量	399.23
分子式	C21H23BFNO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-fluorobenzyl (1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborole-6-carbonyl)-l-valinate

参考文献

1. Akama T, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):6-10.

AN11736

生物&药学活性

物理化学性质&存储条件

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AN11736

生物&药学活性

物理化学性质&存储条件

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