ALDH2 activator Z17

Chemical Structure : ALDH2 activator Z17

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货号: PC-26320Not For Human Use, Lab Use Only.

ALDH2 activator Z17 is a small molecule aldehyde dehydrogenase 2 (ALDH2) activator with EC50 of 16.4 uM and ALDH2 maximum activation fold of 5.4.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ALDH2 activator Z17 is a small molecule aldehyde dehydrogenase 2 (ALDH2) activator with EC50 of 16.4 uM and ALDH2 maximum activation fold of 5.4.
Z17 exhibited significantly efficacy not only in enhancing cardiac function but also in mitigating myocardial necrosis on myocardial I/R injured mice.

物理化学性质&存储条件

分子量	430.86
分子式	C21H20ClFN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, 2-chloro-6-(cyclopropylmethoxy)-N-[(3-fluoro-4-methoxyphenyl)methyl]-3-(4H-1,2,4-triazol-4-yl)-

参考文献

1. Fengping Zhao, et al. ACS Med Chem Lett. 2025 Jun 9;16(7):1420-1427.