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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-AKB-6899
AKB-6899

Chemical Structure : AKB-6899

CAS No.: 1007377-55-0

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AKB-6899 (AKB6899)

货号: PC-26202Not For Human Use, Lab Use Only.

AKB-6899 is a small molecule prolyl hydroxylase domain 3 (PHD3) inhibitor and selective HIF-2α stabilizer, enhances monocyte and macrophage production of sVEGFR-1.

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5 mg ￥980 In stock
10 mg ￥1580 In stock
25 mg ￥2780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AKB-6899 is a small molecule prolyl hydroxylase domain 3 (PHD3) inhibitor and selective HIF-2α stabilizer, enhances monocyte and macrophage production of sVEGFR-1.

物理化学性质&存储条件

分子量 290.25
分子式 C14H11FN2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(5-(3-Fluorophenyl)-3-hydroxypicolinoyl)glycine

参考文献

1. Roda JM, et al. J Immunol. 2012 Sep 15;189(6):3168-77.

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