AIP-II

Chemical Structure : AIP-II

CAS No.: 200010-31-7

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货号: PC-26865Not For Human Use, Lab Use Only.

AIP-II is a peptidomimetic inhibitor of staphylococcus aureus AgrC quorum sensing receptors, inhibits AgrC-III in methicillin-resistant type III Staphylococcus aureus strain AH1747 with IC50 of 0.532 nM, binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus.

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生物&药学活性

物理化学性质&存储条件

分子量	878.99
分子式	C38H58N10O12S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Phenylalanine, glycyl-L-valyl-L-asparaginyl-L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-, (9→5)-thiolactone

参考文献

1. Wang B, et al. Mol Cell. 2014 Mar 20;53(6):929-40.

2. Olson ME, et al. J Bacteriol. 2014 Oct;196(19):3482-93.

3. Brown MM, et al. Antimicrob Agents Chemother. 2020 May 21;64(6):e00172-20.

4. Vasquez JK, et al. Chembiochem. 2017 Feb 16;18(4):413-423.

AIP-II

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AIP-II

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