ADAM17 inhibitor 2155-17

Chemical Structure : ADAM17 inhibitor 2155-17

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货号: PC-25431Not For Human Use, Lab Use Only.

ADAM17 inhibitor 2155-17 is a specific small molecule ADAM17 inhibitor with IC50 of 4.3 uM, with no activity against MMP2, MMP8, MMP9 ,MMP14, and ADAM10 (IC50>100 uM).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ADAM17 inhibitor 2155-17 is a specific small molecule ADAM17 inhibitor with IC50 of 4.3 uM, with no activity against MMP2, MMP8, MMP9 ,MMP14, and ADAM10 (IC50>100 uM).

物理化学性质&存储条件

分子量	669.91
分子式	C40H55N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-benzyl-1-((R)-1-cyclohexyl-3-((S)-2-(((S)-2,3-dioxo-6-propylpiperazin-1-yl)methyl)pyrrolidin-1-yl)propan-2-yl)-4-phenethylpiperazine-2,3-dione

参考文献

1. Jaiswal AK, et al. Sci Rep. 2025 Aug 25;15(1):31253.

2. Knapinska AM, et al. J Med Chem. 2015 Aug 13;58(15):5808-24.