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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-ACY-1083
ACY-1083

Chemical Structure : ACY-1083

CAS No.: 1708113-43-2

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ACY-1083 (ACY1083)

货号: PC-24775Not For Human Use, Lab Use Only.

ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms.

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2 mg ￥1880 In stock
5 mg ￥2980 In stock
10 mg ￥4980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms.

物理化学性质&存储条件

分子量 348.35
分子式 C17H18F2N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((4,4-Difluoro-1-phenylcyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide

参考文献

1. Barbara Vergani, et al. J Med Chem. 2019 Dec 12;62(23):10711-10739.

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