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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-11β-HSD-ABT-384
ABT-384

Chemical Structure : ABT-384

CAS No.: 868623-40-9

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ABT-384 (ABT384)

货号: PC-21935Not For Human Use, Lab Use Only.

ABT-384 is a potent and selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with Ki values of 0.1-2.7 nM against rodent, monkey, and human 11β-HSD1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ABT-384 is a potent and selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with Ki values of 0.1-2.7 nM against rodent, monkey, and human 11β-HSD1.

物理化学性质&存储条件

分子量 493.58
分子式 C25H34F3N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Piperazineacetamide, N-[5-(aminocarbonyl)tricyclo[3.3.1.13,7]dec-2-yl]-alpha,alpha-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-,

参考文献

1. An G, et al. Drug Metab Dispos. 2013 May;41(5):1035-45.

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