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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-ABD0171
ABD0171

Chemical Structure : ABD0171

CAS No.: 2595201-23-1

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ABD0171 (ABD-0171)

货号: PC-25912Not For Human Use, Lab Use Only.

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

物理化学性质&存储条件

分子量 333.49
分子式 C19H27NO2S:
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Pentynethioic acid, 4-[[2-[(3,4-dimethylphenyl)methoxy]ethyl]methylamino]-4-methyl-, S-methyl ester

参考文献

1. Pequerul R, et al. Cell Chem Biol. 2025 Oct 16;32(10):1260-1278.e12.

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