ABC transporter modulator-4 | ABCC6 modulator | Probechem Biochemicals

Chemical Structure : ABC transporter modulator-4

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ABC transporter modulator-4 (ABCC6 positive functional modulator)

货号: PC-28079Not For Human Use, Lab Use Only.

ABC transporter modulator-4 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

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ABC transporter modulator-4 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

物理化学性质&存储条件

分子量	425.32
分子式	C19H18Cl2N2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-6-chloro-N-(1-(3-chloro-4-(methylsulfonyl)phenyl)ethyl)-1-methyl-1H-indole-2-carboxamide

参考文献

1. Patent WO2025129023 A1.

ABC transporter modulator-4 (ABCC6 positive functional modulator)

生物&药学活性

物理化学性质&存储条件

参考文献

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ABC transporter modulator-4 (ABCC6 positive functional modulator)

生物&药学活性

物理化学性质&存储条件

参考文献

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