ABC transporter modulator-3 | ABCC6 modulator | Probechem Biochemicals

Chemical Structure : ABC transporter modulator-3

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ABC transporter modulator-3 (ABCC6 positive functional modulator)

货号: PC-28078Not For Human Use, Lab Use Only.

ABC transporter modulator-3 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

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ABC transporter modulator-3 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

物理化学性质&存储条件

分子量	480.97
分子式	C24H21ClN4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5'-chloro-6-(mesityloxy)-[2,3'-bipyridin]-5-yl)pyridine-3-sulfonamide

参考文献

1. Patent WO2025151724 A1 2025-07-17.

ABC transporter modulator-3 (ABCC6 positive functional modulator)

生物&药学活性

物理化学性质&存储条件

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ABC transporter modulator-3 (ABCC6 positive functional modulator)

生物&药学活性

物理化学性质&存储条件

参考文献

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