ABC transporter modulator-2 | ABCC6 modulator | Probechem Biochemicals

Chemical Structure : ABC transporter modulator-2

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ABC transporter modulator-2 (ABCC6 modulator)

货号: PC-28077Not For Human Use, Lab Use Only.

ABC transporter modulator-2 is a potent positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6, ABCB4, and ABCA4 P1380L with EC50 of <1 uM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ABC transporter modulator-2 is a potent positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6, ABCB4, and ABCA4 P1380L with EC50 of <1 uM.

物理化学性质&存储条件

分子量	464.42
分子式	C19H15F3N6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5'-cyano-6-((4,6-dimethyl-2-(trifluoromethyl)pyrimidin-5-yl)oxy)-[2,3'-bipyridin]-5-yl)methanesulfonamide

参考文献

1. Patent WO2025151724 A1 2025-07-17.