Tegeprotafib (ABBV-CLS-579) | PTP1B/PTPN2 inhibitor | Probechem Biochemicals

Chemical Structure : ABBV-CLS-579

CAS No.: 2407610-46-0

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ABBV-CLS-579 (Tegeprotafib)

货号: PC-23059Not For Human Use, Lab Use Only.

Tegeprotafib (ABBV-CLS-579) is a potent, selective orally active PTP1B/PTPN2 inhibitor with IC50 of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively

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5 mg	￥5280	In stock
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生物&药学活性

Tegeprotafib (ABBV-CLS-579) is a potent, selective orally active PTP1B/PTPN2 inhibitor with IC50 of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively

物理化学性质&存储条件

分子量	326.30
分子式	C13H11FN2O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,2,5-Thiadiazolidin-3-one, 5-(1-fluoro-3-hydroxy-7-methoxy-2-naphthalenyl)-, 1,1-dioxide

参考文献

1. Patent WO2019246513A1.

ABBV-CLS-579 (Tegeprotafib)

生物&药学活性

物理化学性质&存储条件

参考文献

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ABBV-CLS-579 (Tegeprotafib)

生物&药学活性

物理化学性质&存储条件

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