A 834735 |CAS:895155-57-4 Probechem Biochemicals

Chemical Structure : A 834735

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A 834735 (A-834735;A834735)

货号: PC-60764Not For Human Use, Lab Use Only.

A 834735 is a potent, nonselective, brain penetrant, full agonist at both the central CB1 and peripheral CB2 receptors with Ki of 4.6 and 0.31 nM, respectively.

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生物&药学活性

A 834735 is a potent, nonselective, brain penetrant, full agonist at both the central CB1 and peripheral CB2 receptors with Ki of 4.6 and 0.31 nM, respectively.
A 834735 reverses thermal hyperalgesia without adverse side effects in a rat neuropathic pain model.

物理化学性质&存储条件

分子量	339.5
分子式	C22H29NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	[1-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone

参考文献

1. Chin CL, et al. Br J Pharmacol. 2008 Jan;153(2):367-79.

2. Grim TW, et al. J Pharmacol Exp Ther. 2016 Nov;359(2):329-339.

A 834735 (A-834735;A834735)

生物&药学活性

物理化学性质&存储条件

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A 834735 (A-834735;A834735)

生物&药学活性

物理化学性质&存储条件

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