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首页-小分子抑制剂&激动剂-GPCR-Adrenergic Receptor-A-61603
A-61603

Chemical Structure : A-61603

CAS No.: 107756-30-9

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A-61603 (A61603)

货号: PC-26581Not For Human Use, Lab Use Only.

A-61603 is a potent, selective alpha 1-adrenergic receptor (α1A AR) agonist, >35-fold more potent at α1A than at α1B or α1D sites, induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro with EC50 of 6.9 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A-61603 is a potent, selective alpha 1-adrenergic receptor (α1A AR) agonist, >35-fold more potent at α1A than at α1B or α1D sites, induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro with EC50 of 6.9 nM.

物理化学性质&存储条件

分子量 390.30
分子式 C14H20BrN3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanesulfonamide hydrobromide

参考文献

1. Knepper SM, et al. J Pharmacol Exp Ther. 1995 Jul;274(1):97-103.

2. Buckner SA, et al. Eur J Pharmacol. 1996 Feb 22;297(3):241-8.

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