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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-6H05 trifluoroacetate
6H05 trifluoroacetate

Chemical Structure : 6H05 trifluoroacetate

CAS No.: 2061344-88-3

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6H05 trifluoroacetate (K-Ras inhibitor, 6H05 TFA)

货号: PC-43022Not For Human Use, Lab Use Only.

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors..

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5 mg ￥1280 In stock
10 mg ￥1880 In stock
25 mg ￥3280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.

物理化学性质&存储条件

分子量 590.1425
分子式 C22H31ClF3N3O4S3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
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Solubility

DMSO: ≥ 51 mg/mL
Chemical Name/SMILES

4-Piperidinecarboxamide, 1-[2-[(4-chlorophenyl)thio]acetyl]-N-[2-[[2-(dimethylamino)ethyl]dithio]ethyl]-, 2,2,2-trifluoroacetic acid

参考文献

1. Ostrem JM, et al. Nature. 2013 Nov 28;503(7477):548-51.

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