5-O-Methylvisammioside | HMGB1 inhibitor, CNT2 inhibitor

Chemical Structure : 5-O-Methylvisammioside

CAS No.: 84272-85-5

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5-O-Methylvisammioside (5OMV)

货号: PC-25387Not For Human Use, Lab Use Only.

5-O-Methylvisammioside (5OMV) is a flavonol compound derived from the traditional Chinese medicine plant Saposhnikovia divaricat, inhibits vasospasm induced by High Mobility Group Box 1 (HMGB1) protein, also inhibits intestinal concentrative nucleoside transporter 2 (CNT2) with IC50 of 11.22 uM, inhibits intestinal purine nucleoside absorption.

规格	价格	库存
5 mg	￥380	In stock
10 mg	￥580	In stock
25 mg	￥880	In stock
50 mg	￥1280	In stock
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	452.46
分子式	C22H28O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-Methoxy-7-methyl-2-(2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-2,3-dihydro-5H-furo[3,2-g]chromen-5-one

参考文献

1. Hou W, et al. PLoS One. 2025 May 5;20(5):e0322056.

2. Mai S, et al. Biochem Pharmacol. 2025 Aug 13:117236.

5-O-Methylvisammioside (5OMV)

生物&药学活性

物理化学性质&存储条件

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5-O-Methylvisammioside (5OMV)

生物&药学活性

物理化学性质&存储条件

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