4-P-PDOT | Melatonin receptor MT2 antagonist | Probechem Biochemicals

Chemical Structure : 4-P-PDOT

CAS No.: 134865-74-0

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4-P-PDOT (4-phenyl-2-propionamidotetralin)

货号: PC-26838Not For Human Use, Lab Use Only.

4-P-PDOT is a potent, selective and high affinity melatonin receptor MT2 antagonist with pEC50 of 8.72 inhibition of forskolin stimulated cyclic AMP, >300-fold more selective for MT2 than MT1.

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生物&药学活性

4-P-PDOT is a potent, selective and high affinity melatonin receptor MT2 antagonist with pEC50 of 8.72 inhibition of forskolin stimulated cyclic AMP, >300-fold more selective for MT2 than MT1.

物理化学性质&存储条件

分子量	279.38
分子式	C19H21NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide

参考文献

1. Browning C, et al. Br J Pharmacol. 2000 Mar;129(5):877-86.

4-P-PDOT (4-phenyl-2-propionamidotetralin)

生物&药学活性

物理化学性质&存储条件

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4-P-PDOT (4-phenyl-2-propionamidotetralin)

生物&药学活性

物理化学性质&存储条件

参考文献

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