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4-Demethylepipodophyllotoxin

Chemical Structure : 4-Demethylepipodophyllotoxin

CAS No.: 6559-91-7

4-Demethylepipodophyllotoxin (4'-O-demethylepipodophyllotoxin, 4'-DMEP)

货号: PC-45256Not For Human Use, Lab Use Only.

4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

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100 mg ¥780 In stock
500 mg ¥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

物理化学性质&存储条件

分子量 400.3787
分子式 C21H20O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-

参考文献

1. Dhawan D, et al. Carcinogenesis. 1999 Jun;20(6):997-1003.

2. Gewirtz DA. Cancer Res. 1985 Dec;45(12 Pt 1):6290-2.

3. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8.

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