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首页-小分子抑制剂&激动剂-Others-Other Targets-3,4,3-LI(1,2-HOPO)
3,4,3-LI(1,2-HOPO)

Chemical Structure : 3,4,3-LI(1,2-HOPO)

CAS No.: 110874-36-7

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3,4,3-LI(1,2-HOPO) (Enfipaxetan, HOPO 14-1)

货号: PC-27422Not For Human Use, Lab Use Only.

3,4,3-LI(1,2-HOPO) (Enfipaxetan) is a metal chelating agent, exhibits extremely high affinity for lanthanide metal ions, sensitizes the emission of Sm(III), Eu(III), and Tb(III) in the Visible range and the emission of Pr(III), Nd(III), Sm(III), and Yb(III).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

3,4,3-LI(1,2-HOPO) (Enfipaxetan) is a metal chelating agent, exhibits extremely high affinity for lanthanide metal ions, sensitizes the emission of Sm(III), Eu(III), and Tb(III) in the Visible range and the emission of Pr(III), Nd(III), Sm(III), and Yb(III).

物理化学性质&存储条件

分子量 750.72
分子式 C34H38N8O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N,N'-(butane-1,4-diyl)bis(1-hydroxy-N-(3-(1-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamido)propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide)

参考文献

1. Sturzbecher-Hoehne M, et al. 3,4,3-LI(1,2-HOPO): in vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation. Dalton Trans. 2011 Sep 7;40(33):8340-6.

2. Xu J, et al. J Med Chem. 1995 Jul 7;38(14):2606-14.

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