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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Eukaryotic Initiation Factor (eIF)-1Ai-4927
1Ai-4927

Chemical Structure : 1Ai-4927

CAS No.: 475108-18-0

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1Ai-4927

货号: PC-24688Not For Human Use, Lab Use Only.

1Ai-4927 is a specific inhibitor of ribosomal protein Rps10 with IC50 of 6.1 uM, targets the eIF1A-RPS10 complex,1Ai-4927 binds only RPS10, but not affect eIF1A.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

1Ai-4927 is a specific inhibitor of ribosomal protein Rps10 with IC50 of 6.1 uM, targets the eIF1A-RPS10 complex,1Ai-4927 binds only RPS10, but not affect eIF1A.

物理化学性质&存储条件

分子量 454.87
分子式 C22H19ClN4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-3-(5-methylisoxazol-3-yl)urea

参考文献

1. Hayat D, et al. EMBO J. 2025 May 12. doi: 10.1038/s44318-025-00449-6.

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