Chemical Structure : 14-3-3-ERα stabilizer 41
货号: PC-25264Not For Human Use, Lab Use Only.
14-3-3/ERα stabilizer 41 is a potent, selective and covalent small-molecule stabilizer of the 14-3-3σ/ERα complex, forms a covalent bond with C38 of 14-3-3σ, shows remarkable selectivity for 14-3-3σ/ERα (KD=10.1 nM).
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14-3-3/ERα stabilizer 41 is a potent, selective and covalent small-molecule stabilizer of the 14-3-3σ/ERα complex, forms a covalent bond with C38 of 14-3-3σ, shows remarkable selectivity for 14-3-3σ/ERα (KD=10.1 nM).
分子量 | 436.92 | |
分子式 | C24H22ClFN4O | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Konstantinidou M, et al. Nat Commun. 2025 Jul 14;16(1):6467.
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