14-3-3-ERα stabilizer 127 | CAS 3057296-45-1 | Probechem Biochemicals

Chemical Structure : 14-3-3-ERα stabilizer 127

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14-3-3-ERα stabilizer 127 (14-3-3/ERα stabilizer)

货号: PC-25262Not For Human Use, Lab Use Only.

14-3-3/ERα stabilizer 127 is a potent, covalent, small-molecule stabilizer of the 14-3-3σ/ERα complex with EC50 of 2.0 uM, forms a covalent bond with C38 of 14-3-3σ.

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14-3-3/ERα stabilizer 127 is a potent, covalent, small-molecule stabilizer of the 14-3-3σ/ERα complex with EC50 of 2.0 uM, forms a covalent bond with C38 of 14-3-3σ.

物理化学性质&存储条件

分子量	428.35
分子式	C20H27Cl2N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-N-((1-(4-((4-chlorophenyl)amino)tetrahydro-2H-pyran-4-carbonyl)piperidin-4-yl)methyl)acetamide

参考文献

1. Konstantinidou M, et al. J Am Chem Soc. 2023 Sep 20;145(37):20328-20343.

14-3-3-ERα stabilizer 127 (14-3-3/ERα stabilizer)

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14-3-3-ERα stabilizer 127 (14-3-3/ERα stabilizer)

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