11β-HSD1-IN-12

Chemical Structure : 11β-HSD1-IN-12

CAS No.: 872506-67-7

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货号: PC-35575Not For Human Use, Lab Use Only.

11β-HSD1-IN-12 is a potent, selective, oral 11β-HSD1 inhibitor (IC50=1.1 nM) with high selectivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.

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11β-HSD1-IN-12 is a potent, selective, oral 11β-HSD1 inhibitor (IC50=1.1 nM) with high selectivity over other dehydrogenases, glucocorticoid and mineralocorticoid receptors.

物理化学性质&存储条件

分子量	398.946
分子式	C19H27ClN2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-((3-Chloro-2-methylphenyl)sulfonyl)-N-cyclohexylpiperidine-3-carboxamide

参考文献

1. Rosenstock J, et al. Diabetes Care. 2010 Jul;33(7):1516-22.

2. Ge R, et al. Curr Med Chem. 2010;17(5):412-22.

3. Anagnostis P, et al. Metabolism. 2013 Jan;62(1):21-33.

11β-HSD1-IN-12

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