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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-(S)-CE-123
(S)-CE-123

Chemical Structure : (S)-CE-123

CAS No.: 2378384-49-5

(S)-CE-123 (S-CE-123)

货号: PC-21534Not For Human Use, Lab Use Only.

(S)-CE-123 is a specific small molecule dopamine transporter (DAT) inhibitor with EC50 of 2.76 uM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    (S)-CE-123 is a specific small molecule dopamine transporter (DAT) inhibitor with EC50 of 2.76 uM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT.
    (S)-CE-123  improves memory acquisition and memory retrieval.

    物理化学性质&存储条件

    分子量 313.43
    分子式 C17H15NOS2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-[[(S)-(Diphenylmethyl)sulfinyl]methyl]thiazole

    参考文献

    1. Nikiforuk A., et al. Front. Behav. Neurosci. 11:222.

    2. Rotolo RA, et al. Front Pharmacol. 2019 Jun 28;10:682.

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