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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Topoisomerase-(S)-10-Hydroxycamptothecin
(S)-10-Hydroxycamptothecin

Chemical Structure : (S)-10-Hydroxycamptothecin

CAS No.: 19685-09-7

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(S)-10-Hydroxycamptothecin (10-HCPT)

货号: PC-25441Not For Human Use, Lab Use Only.

(S)-10-Hydroxycamptothecin (10-HCPT, 10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor with remarkable apoptosis-inducing effect, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration.

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500 mg ￥280 In stock
1 g ￥380 In stock
5 g Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

(S)-10-Hydroxycamptothecin (10-HCPT, 10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor with remarkable apoptosis-inducing effect, also is a potent DHHC9 inhibitor that effectively suppressed adenocarcinoma cell migration.

物理化学性质&存储条件

分子量 364.36
分子式 C20H16N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

参考文献

1. Tian Y, et al. J Cell Mol Med. 2025 Sep;29(17):e70815.

2. Zhang XW, et al. Acta Pharmacol Sin. 2000 Apr;21(4):364-8.

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