(R)-PG648 | D3R antagonist | Probechem Biochemicals

Chemical Structure : (R)-PG648

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(R)-PG648 (Compound R-22)

货号: PC-27836Not For Human Use, Lab Use Only.

(R)-PG648 (Compound R-22) is a potent, selective dopamine D3 receptor (D3R) antagonist with Ki of 1.12 nM, 400-fold more selective for D3R over D2R.

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生物&药学活性

(R)-PG648 (Compound R-22) is a potent, selective dopamine D3 receptor (D3R) antagonist with Ki of 1.12 nM, 400-fold more selective for D3R over D2R.

物理化学性质&存储条件

分子量	461.39
分子式	C23H26Cl2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)1H-indole-2-carboxamide

参考文献

1. Ellen Y T Chien, et al. Science. 2010 Nov 19;330(6007):1091-5.

2. Vivek Kumar, et al. ACS Med Chem Lett. 2014 Mar 24;5(6):647-51.

3. Newman AH, et al. J. Med. Chem. 2009;52:2559.

(R)-PG648 (Compound R-22)

生物&药学活性

物理化学性质&存储条件

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(R)-PG648 (Compound R-22)

生物&药学活性

物理化学性质&存储条件

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