Chemical Structure : (D)PPA-1 TFA
CAS No.:
货号: PC-28254Not For Human Use, Lab Use Only.
(D)PPA-1 TFA ((D)-PPA 1 TFA) is a hydrolysis-resistant D-peptide antagonist of PD-1/PD-L1 interaction, binds PD-L1 at an affinity of 0.51 uM in vitro, inhibits PD-1/PD-L1 pathway in vivo.
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|---|---|---|---|
| 5 mg | ¥2180 | In stock | |
| 10 mg | ¥3480 | In stock | |
| 25 mg | ¥5480 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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(D)PPA-1 TFA ((D)-PPA 1 TFA) is a hydrolysis-resistant D-peptide antagonist of PD-1/PD-L1 interaction, binds PD-L1 at an affinity of 0.51 uM in vitro, inhibits PD-1/PD-L1 pathway in vivo.
| 分子量 | 1669.67 | |
| 分子式 | C72H99F3N20O23 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
D-{Asn-Tyr-Ser-Lys-Pro-Thr-Asp-Arg-Gln-Tyr-His-Phe} TFA salt |
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1. Chang HN, et al. Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11760-4.
2. Feng Y, et al. Biomaterials. 2021 Aug;275:120990.
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