(D)PPA-1 ((D)-PPA 1) | PD-L1 antagonist | Probechem Biochemicals

Chemical Structure : (D)PPA-1

CAS No.: 1620813-53-7

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(D)PPA-1 ((D) PPA-1, (D)PPA 1)

货号: PC-28253Not For Human Use, Lab Use Only.

(D)PPA-1 ((D)-PPA 1) is a hydrolysis-resistant D-peptide antagonist of PD-1/PD-L1 interaction, binds PD-L1 at an affinity of 0.51 uM in vitro, inhibits PD-1/PD-L1 pathway in vivo.

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10 mg	￥3480	In stock
25 mg	￥5480	In stock
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生物&药学活性

(D)PPA-1 ((D)-PPA 1) is a hydrolysis-resistant D-peptide antagonist of PD-1/PD-L1 interaction, binds PD-L1 at an affinity of 0.51 uM in vitro, inhibits PD-1/PD-L1 pathway in vivo.

物理化学性质&存储条件

分子量	1555.65
分子式	C70H98N20O21
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	D-{Asn-Tyr-Ser-Lys-Pro-Thr-Asp-Arg-Gln-Tyr-His-Phe}

参考文献

1. Chang HN, et al. Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11760-4.

2. Feng Y, et al. Biomaterials. 2021 Aug;275:120990.

(D)PPA-1 ((D) PPA-1, (D)PPA 1)

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物理化学性质&存储条件

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(D)PPA-1 ((D) PPA-1, (D)PPA 1)

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物理化学性质&存储条件

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